| Identification | Back Directory | [Name]
Nivalenol-13C15 solution | [CAS]
911392-40-0 | [Synonyms]
13C15-Nivalenol
Nivalenol-13C15 solution
13C15]-Nivalenol-25 μg/mL in ACN | [EINECS(EC#)]
804-499-3 | [Molecular Formula]
C15H20O7 | [MDL Number]
MFCD26142914 | [MOL File]
911392-40-0.mol | [Molecular Weight]
327.2 |
| Hazard Information | Back Directory | [Uses]
Nivalenol-13C15 is the 13C labeled Nivalenol (HY-N6801)[1]. Nivalenol, classified as type B trichotecenes toxins produced by Fusarium graminearum, is a fungal metabolite present in agricultural product[2]. Nivalenol induces cell death through caspase-dependent mechanisms and via the intrinsic apoptotic pathway. Nivalenol affects the immune system, causes emesis, growth retardation, reproductive disorders and has a haematotoxic/myelotoxic effect[3]. | [storage]
Store at -20°C | [References]
[1] Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-220. DOI:10.1177/1071100718790255
[2] Bry?a M, et al. Natural Occurrence of Nivalenol, Deoxynivalenol, and Deoxynivalenol-3-Glucoside in Polish Winter Wheat. Toxins (Basel). 2018 Feb 13;10(2). DOI:10.3390/toxins10020081
[3] Aupanun S, et al. Individual and combined mycotoxins deoxynivalenol, nivalenol, and fusarenon-X induced apoptosis in lymphoid tissues of mice after oral exposure. Toxicon. 2019 Jul;165:83-94. DOI:10.1016/j.toxicon.2019.04.017 |
|
| Company Name: |
ChemeGen
|
| Tel: |
18818260767 |
| Website: |
https://www.chemegen.com |
|