ChemicalBook--->CAS DataBase List--->914361-76-5

914361-76-5

914361-76-5 Structure

914361-76-5 Structure
IdentificationBack Directory
[CAS]

914361-76-5
[Molecular Formula]

C29H29N3O4
[Molecular Weight]

483.56
Chemical PropertiesBack Directory
[Melting point ]

171-173 °C
[density ]

1.259±0.06 g/cm3(Predicted)
[pka]

9.51±0.10(Predicted)
[InChIKey]

SINOYLIIFJJPCM-IZZNHLLZSA-N
[SMILES]

C1(=O)N([C@@H]2O[C@H](CO)CN(C(C3=CC=CC=C3)(C3=CC=CC=C3)C3=CC=CC=C3)C2)C=C(C)C(=O)N1
Safety DataBack Directory
[Symbol(GHS) ]

Exclamation Mark (GHS07)
GHS07
[Signal word ]

Warning
[Hazard statements ]

H302-H315-H319
[Precautionary statements ]

P501-P270-P264-P280-P302+P352-P337+P313-P305+P351+P338-P362+P364-P332+P313-P301+P312+P330
[REACH Registrations]

Active
Hazard InformationBack Directory
[Description]

7'-OH-N-trityl Morpholino thyMine (PMO Thymidine Precusor) is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibiting DNA synthesis, induction of apoptosis, etc.
[Uses]

7’-OH-N-trityl morpholinothymine (PMO Thymidine Precusor) is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].
[References]

[1] Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18(23):3373-88. DOI:10.2174/138161212801227005
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