| Identification | Back Directory | [Name]
Ornipressin Acetate | [CAS]
914453-98-8 | [Synonyms]
Orpressin
Ornipressin Acetate（3397-23-7，free）
Ornipressin Acetate（3397 23 7，free）,Ornipressin Acetate（3397237，free） | [Molecular Formula]
C47H67N13O14S2 | [MOL File]
914453-98-8.mol | [Molecular Weight]
1102.25 |
| Chemical Properties | Back Directory | [storage temp. ]
-20°C | [solubility ]
DMSO: 10 mg/mlPBS (pH 7.2): 20 mg/ml | [form ]
powder | [color ]
white to off-white | [Sequence]
Cys-Tyr-Phe-Gln-Asn-Cys-Pro-{Orn}-Gly-NH2 (Disulfide bridge: Cys1-Cys6) |
| Hazard Information | Back Directory | [Uses]
An acetate salt of ornipressin, a pharmaceutical peptide used as a vasoconstrictor in the treatment of type 1 hepatorenal syndrome. | [Biological Activity]
Ornipressin is a potent vasoconstrictor agent used in surgery for hemostasis and in regional anesthesia for prolongation of nerve block. Ornipressin is a vasopressin agonist specific for the V1 receptor with low antidiuretic activity. | [References]
[1] P. KAM T. T. The pharmacology of ornipressin (POR–8): a local vasoconstrictor used in surgery[J]. European Journal of Anaesthesiology, 2004, 15 2: 133-139. DOI: 10.1111/j.0265-0215.1998.00247.x
[2] KAZIMIERZ WIŚNIEWSKI*. New, Potent, Selective, and Short-Acting Peptidic V1a Receptor Agonists[J]. Journal of Medicinal Chemistry, 2011, 54 13: 4388-4398. DOI: 10.1021/jm200278m |
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| Company Name: |
Merck KGaA
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21-20338288 |
| Website: |
www.sigmaaldrich.cn |
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