| Identification | Back Directory | [Name]
HECOGENIN ACETATE | [CAS]
915-35-5 | [Synonyms]
HECOGENIN ACETATE
HECOGENIN ALCOHOL
(-)-HECOGENIN ACETATE, TECH., 90%
(25R)-3β-Acetoxy-5α-spirostane-12-one
(25R)-3β-Acetyloxy-5α-spirostan-12-one
Hecogenin acetate,()-Hecogenin acetate
(22R,25R)-3β-Acetoxy-5α-spirostane-12-one
12-oxo-5-alpha-spirostan-3-beta-yl acetate
(25R)-3β-Hydroxy-5α-spirostane-12-one=acetate
25R,5ALPHA-SPIROSTAN-3BETA-OL-12-ONE 3-ACETATE
5-ALPHA, 20-ALPHA, 22-ALPHA, 25D-SPIROSTAN-3-BETA-OL-12-ONE ACETATE | [EINECS(EC#)]
213-021-7 | [Molecular Formula]
C29H44O5 | [MDL Number]
MFCD00005088 | [MOL File]
915-35-5.mol | [Molecular Weight]
472.66 |
| Chemical Properties | Back Directory | [Melting point ]
246-248 °C (dec.)(lit.)
| [refractive index ]
-4 ° (C=1, Dioxane) | [storage temp. ]
Refrigerator | [solubility ]
Chloroform (Sparingly), Dioxane (Sparingly, Heated), Ethyl Acetate (Slightly, Heated) | [form ]
Solid | [color ]
White |
| Hazard Information | Back Directory | [Description]
Hecogenin acetate is a steroid sapogenin and an acetylated form of hecogenin that has anthelmintic and antinociceptive properties. It reduces the percentage of mobile larvae in goat fecal cultures containing Haemonchus, Oesophagostomum, and Trichostrongylus nematodes (EC50 = 0.49 mg/ml). Hecogenin acetate (5, 10, or 20 mg/kg, i.p.) inhibits development of mechanical hyperalgesia induced by carrageenan, TNF-α, dopamine , and prostaglandin E2 (PGE2; ) in mice. It also increases latency to tail withdrawal in the tail flick test and has no effect on motor performance in the rotarod test in mice when administered at a dose of 40 mg/kg. | [Uses]
Hecogenin Acetate, is a derivative of Hecogenin (H129945), which is a sapogenin present in the leaves of species from the Agave genus, possessing wide spectrum of pharmacology activities, such as having antinociceptive properties. | [Definition]
ChEBI: HECOGENIN ACETATE is a triterpenoid. | [Purification Methods]
Crystallise the acetate from MeOH. [Beilstein 19 IV 2583.] |
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Energy Chemical
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