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91524-16-2

91524-16-2 Structure

91524-16-2 Structure
IdentificationBack Directory
[Synonyms]

(-) S Timolol
(-)-S-Timolol
Timolol hemihydrate
(S)-timolol hemihydrate
[MOL File]

91524-16-2.mol
Safety DataBack Directory
[Signal word ]

Warning
[Hazard statements ]

H351-H302-H319
[Precautionary statements ]

P201-P202-P281-P308+P313-P405-P501-P264-P270-P301+P312-P330-P501-P264-P280-P305+P351+P338-P337+P313P
Hazard InformationBack Directory
[Definition]

ChEBI: (S)-timolol hemihydrate is a hydrate, which is the hemihydrate form of the (S)-(-) (more active) enantiomer of timolol. It has a role as an antihypertensive agent, an anti-arrhythmia drug, a beta-adrenergic antagonist and an antiglaucoma drug. It contains a (S)-timolol (anhydrous).
[in vivo]

Timolol (hemihydrate) (5 mg/kg daily for 12-week) has a cardioprotective effect via inhibition of ERS response in diabetic rats[3].

Animal Model:Male Wistar rats[3].
Dosage:5 mg/kg
Administration:Timolol (5 mg/kg daily for 12-week)
Result:Showed cardioprotective effect.
[IC 50]

β adrenergic receptor
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