| Identification | Back Directory | [Name]
BENZYL 4-HYDRAZINYLPIPERIDINE-1-CARBOXYLATE DIHYDROCHLORIDE | [CAS]
916831-70-4 | [Synonyms]
Benzyl 4-hydrazinylpiperidine-1-carboxylate hydrochloride
BENZYL 4-HYDRAZINYLPIPERIDINE-1-CARBOXYLATE DIHYDROCHLORIDE
4-Hydrazino-piperidine-1-carboxylic acid benzyl ester hydrochloride
4-Hydrazino-piperidine-1-carboxylic acid benzyl ester dihydrochloride
4-Hydrazinyl-1-piperidinecarboxylic acid phenylmethyl ester hydrochloride (1:1)
Piperidine-1-carboxylic acid, 4-hydrazinyl-, phenylMethyl ester, dihydrochloride | [Molecular Formula]
C13H19N3O2.2ClH | [MDL Number]
MFCD11974914 | [MOL File]
916831-70-4.mol | [Molecular Weight]
322.234 |
| Questions And Answer | Back Directory | [Uses]
Benzyl 4-hydrazinopiperidine-1-carboxylate dihydrochloride is a heterocyclic compound that can be used as a pharmaceutical synthesis intermediate. |
| Hazard Information | Back Directory | [Synthesis]
Step 4: Preparation of benzyl 4-hydrazinylpiperidine-1-carboxylate dihydrochloride. Benzyl 4-(2-(tert-butoxycarbonyl)hydrazinylpiperidine-1-carboxylate (174 g, 0.5 mol) was dissolved in 2 L of a 50% methanol/4N hydrochloric acid dioxane solution and the reaction was stirred for 48 hours at room temperature. After completion of the reaction, the reaction solution was concentrated in vacuum to give the crude product. The crude product was purified by grinding with warmed dichloromethane to give the final 4-hydrazinylpiperidine-1-carboxylic acid benzyl ester dihydrochloride (131 g, 96% yield). | [References]
[1] Patent: WO2014/68527, 2014, A1. Location in patent: Page/Page column 80 |
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