| Identification | Back Directory | [Name]
1H-Purine-2,6-dione, 3,7-dihydro-3,7-dimethyl-1-[3-(2,3,6,9-tetrahydro-3-methyl-2,6-dioxo-1H-purin-1-yl)propyl]- | [CAS]
917877-86-2 | [Synonyms]
Bisdionin F
1H-Purine-2,6-dione, 3,7-dihydro-3,7-dimethyl-1-[3-(2,3,6,9-tetrahydro-3-methyl-2,6-dioxo-1H-purin-1-yl)propyl]- | [Molecular Formula]
C16H18N8O4 | [MOL File]
917877-86-2.mol | [Molecular Weight]
386.37 |
| Chemical Properties | Back Directory | [Boiling point ]
766.7±70.0 °C(Predicted) | [density ]
1.67±0.1 g/cm3(Predicted) | [storage temp. ]
2-8°C | [solubility ]
DMSO: 5mg/mL, clear, nearly colorless | [form ]
powder | [pka]
8.58±0.70(Predicted) | [color ]
off-white | [InChIKey]
PUHJHZQYIBJCSQ-UHFFFAOYSA-N | [SMILES]
CN(C=N1)C2=C1N(C)C(N(C2=O)CCCN3C(N(C)C(N=CN4)=C4C3=O)=O)=O |
| Hazard Information | Back Directory | [Description]
Bisdionin F is a selective hAMCase Inhibitor. | [Uses]
Bisdionin F is a compound with the ability to restore the antibacterial function of macrophages, which can block the arginase activity induced by Candida albicans and restore the nitric oxide production and antibacterial function of macrophages. | [References]
[1] Candida albicans Chitin Increases Arginase-1 Activity in Human Macrophages, with an Impact on Macrophage Antimicrobial Functions DOI:10.1128/mBio.01820-16 |
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