ChemicalBook--->CAS DataBase List--->91809-67-5

91809-67-5

91809-67-5 Structure

91809-67-5 Structure
IdentificationBack Directory
[Name]

6-Carboxytetramethylrhodamine
[CAS]

91809-67-5
[Synonyms]

6-TAMRA
CS-1310
-4-carboxybenzoate
6-CarboxytetraMethyl
6-CARBOXYTETRAMETHYLRHODAMINE
6-Carboxytetramethylrhodamine, >=99%
6-TAMRA/ [6-Carboxytetramethylrhodamine]
6-CARBOXYTETRAMETHYLRHODAMINE (SINGLE IS
N,N,N',N'-TetraMethyl-6-carboxyrhodaMine
6-Carboxy-tetramethylrhodamine≥ 99% (HPLC)
6-Carboxytetramethylrhodamine, single isomer
6-Carboxytetramethylrhodamine, for fluorescence,≥90%
6-CARBOXY-TETRAMETHYLRHODAMINE, FOR FLUORESCENCE*
6-TAMRA [6-Carboxytetramethylrhodamine] *Single isomer*
6-TAMRA [6-Carboxytetramethylrhodamine] *CAS 91809-67-5*
9-(2,5-Dicarboxyphenyl)-3,6-bis(diMethylaMino)xanthyliuM
2-(3,6-Bis(dimethylamino)xanthylium-9-yl)-4-carboxybenzoate
[Molecular Formula]

C25H22N2O5
[MDL Number]

MFCD00467559
[MOL File]

91809-67-5.mol
[Molecular Weight]

430.45
Chemical PropertiesBack Directory
[Melting point ]

NA
[storage temp. ]

Keep in dark place,Inert atmosphere,2-8°C
[solubility ]

DMSO: soluble
[form ]

A solid
[color ]

Light brown to black
[Appearance]

Purple solid
[ex/em]

550/576 nm (MeOH/PBS)
[ε(extinction coefficient)]

90000 L⋅mol−1⋅cm−1
[Φ(quantum yield)]

0.1
[InChI]

InChI=1S/C25H22N2O5/c1-26(2)15-6-9-18-21(12-15)32-22-13-16(27(3)4)7-10-19(22)23(18)20-11-14(24(28)29)5-8-17(20)25(30)31/h5-13H,1-4H3,(H-,28,29,30,31)
[InChIKey]

COCMHKNAGZHBDZ-UHFFFAOYSA-N
[SMILES]

C(C1C=CC(C(=O)O)=CC=1C1=C2C=CC(N(C)C)=CC2=[O+]C2C=C(N(C)C)C=CC1=2)(=O)[O-]
Safety DataBack Directory
[Symbol(GHS) ]

Exclamation Mark (GHS07)
GHS07
[Signal word ]

Warning
[Hazard statements ]

H315-H319-H335
[Precautionary statements ]

P261-P305+P351+P338
[Safety Statements ]

22-24/25
[WGK Germany ]

3
[F ]

8-10
[HS Code ]

3204 90 00
Raw materials And Preparation ProductsBack Directory
[Raw materials]

Benzoic acid
[Preparation Products]

Tetramethylrhodamine-->TAMRA azide, 5- isomer
Hazard InformationBack Directory
[Description]

6-Carboxytetramethylrhodamine is a fluorescent dye that has commonly been used for the covalent labeling of oligonucleotides for DNA analysis. It displays excitation/emission maxima of 543/572 nm, respectively. 6-Carboxytetramethylrhodamine has been used in various DNA-protein binding studies, DNA FRET experiments, and as a standard reporter or quencher dye in RT-PCR.
[Chemical Properties]

Grey Solid
[Uses]

A long-wavelength dye
[Uses]

Free acid form of 6-carboxytetramethylrhodamine single isomer.
[References]

[1] MAKSIM V. KVACH. Practical Synthesis of Isomerically Pure 5- and 6-Carboxytetramethylrhodamines, Useful Dyes for DNA Probes[J]. Bioconjugate Chemistry Bioconjugate, 2009, 20 8: 1673-1682. DOI: 10.1021/bc900037b
[2] CHENGLING HAN  Lily Z  Tingting Chen. Terbium chelate as donor label in time-resolved fluorescence energy transfer study of DNA hybridization[J]. Chemical Physics Letters, 2010, 500 4: Pages 323-326. DOI: 10.1016/j.cplett.2010.10.028
[Excitation / Emission Maximum]

540 nm/568 nm
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