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91826-20-9

91826-20-9 Structure

91826-20-9 Structure
IdentificationBack Directory
[Name]

GRF (1-29) AMIDE (RAT)
[CAS]

91826-20-9
[Synonyms]

GRF(1-29)NH2【rat】
GRF (1-29) AMIDE (RAT)
GHRF (1-29), AMIDE, RAT
Somatoliberin(1-29)NH2【rat】
Somatoliberin(1-29)amide[rat]
Rat hypothalamic GRF(1-29)-NH2
somatoliberin fragment 1-29 amide, rat
GROWTH HORMONE-RELEASING FACTOR (1-29) AMIDE (RAT)
GROWTH HORMONE RELEASING FACTOR FRAGMENT 1-29 AMIDE RAT
HIS-ALA-ASP-ALA-ILE-PHE-THR-SER-SER-TYR-ARG-ARG-ILE-LEU-GLY-GLN-LEU-TYR-ALA-ARG-LYS-LEU-LEU-HIS-GLU-ILE-MET-ASN-ARG-NH2
H-HIS-ALA-ASP-ALA-ILE-PHE-THR-SER-SER-TYR-ARG-ARG-ILE-LEU-GLY-GLN-LEU-TYR-ALA-ARG-LYS-LEU-LEU-HIS-GLU-ILE-MET-ASN-ARG-NH2
L-His-L-Ala-L-Asp-L-Ala-L-Ile-L-Phe-L-Thr-L-Ser-L-Ser-L-Tyr-L-Arg-L-Arg-L-Ile-L-Leu-Gly-L-Gln-L-Leu-L-Tyr-L-Ala-L-Arg-L-Lys-L-Leu-L-Leu-L-His-L-Glu-L-Ile-L-Met-L-Asn-L-Arg-NH2
HIS-VAL-ASP-ALA-ILE-PHE-THR-THR-ASN-TYR-ARG-LYS-LEU-LEU-SER-GLN-LEU-TYR-ALA-ARG-LYS-VAL-ILE-GLN-ASP-ILE-MET-ASN-LYS-GLN-GLY-GLU-ARG-ILE-GLN-GLU-GLN-ARG-ALA-ARG-LEU-SER: HVDAIFTTNYRKLLSQLYARKVIQDIMNKQGERIQEQRARLS
[Molecular Formula]

C155H251N49O40S
[MDL Number]

MFCD00133384
[MOL File]

91826-20-9.mol
[Molecular Weight]

3473.02
Chemical PropertiesBack Directory
[density ]

1.46±0.1 g/cm3(Predicted)
[storage temp. ]

−20°C
[form ]

Solid
[color ]

White to off-white
[Sequence]

His-Ala-Asp-Ala-Ile-Phe-Thr-Ser-Ser-Tyr-Arg-Arg-Ile-Leu-Gly-Gln-Leu-Tyr-Ala-Arg-Lys-Leu-Leu-His-Glu-Ile-Met-Asn-Arg-NH2
Safety DataBack Directory
[WGK Germany ]

3
Hazard InformationBack Directory
[Uses]

GRF (1-29) amide (rat) is a synthetic peptide which can stimulate the growth hormone (GH) secretion.
[in vivo]

Time course studies of GRF (1-29) amide (rat) disappearance show apparent half-lives of 18±4 min and 13±3 min in serum and liver homogenate, respectively. This is accompanied by the appearance of degradation products that are all less hydrophobic than the native peptide. In the serum, two major metabolites are detected and isolated by preparative HPLC[1].

[References]

[1] Boulanger L, et al. Catabolism of rat growth hormone-releasing factor(1-29) amide in rat serum and liver. Peptides. 1992 Jul-Aug;13(4):681-9. DOI:10.1016/0196-9781(92)90173-z
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