| Identification | Back Directory | [Name]
BenzaMide, 3,5-dichloro-N-[[(3S,4R)-1-(3,3-diMethylbutyl)-3-fluoro-4-piperidinyl]Methyl]- | [CAS]
918333-06-9 | [Synonyms]
TTA-P1
BenzaMide, 3,5-dichloro-N-[[(3S,4R)-1-(3,3-diMethylbutyl)-3-fluoro-4-piperidinyl]Methyl]- | [Molecular Formula]
C19H27Cl2FN2O | [MOL File]
918333-06-9.mol | [Molecular Weight]
389.335 |
| Hazard Information | Back Directory | [Uses]
TTA-P1 is a potent state-independent compound inhibiting human T-type calcium channel. T-type calcium channels play a role in diverse physiological responses including neuronal burst firing, hormone secretion, and cell growth. TTA-P1 has the potential for the research of absence epilepsy[1]. | [References]
[1] Uebele VN, Nuss CE, Fox SV, et al. Positive allosteric interaction of structurally diverse T-type calcium channel antagonists. Cell Biochem Biophys. 2009;55(2):81-93. DOI:10.1007/s12013-009-9057-4 |
|
|