ChemicalBook--->CAS DataBase List--->918629-48-8

918629-48-8

918629-48-8 Structure

918629-48-8 Structure
IdentificationBack Directory
[Name]

Transdermal Peptide
[CAS]

918629-48-8
[Synonyms]

TTD-1
Transdermal Peptide
Transdermal peptide 1, TD-1
Transdermal Peptide USP/EP/BP
Glycine, L-alanyl-L-cysteinyl-L-seryl-L-seryl-L-seryl-L-prolyl-L-seryl-L-lysyl-L-histidyl-L-cysteinyl-
[Molecular Formula]

C40H66N14O16S2
[MDL Number]

MFCD09263396
[MOL File]

918629-48-8.mol
[Molecular Weight]

1063.17
Chemical PropertiesBack Directory
[Boiling point ]

1710.6±65.0 °C(Predicted)
[density ]

1.450±0.06 g/cm3(Predicted)
[storage temp. ]

Store at -20°C
[pka]

3.20±0.10(Predicted)
[Water Solubility ]

Soluble in Water
Hazard InformationBack Directory
[Uses]

TD-1 (Transdermal peptide) is a short peptide that can promote the delivery of macromolecule drugs, especially protein drugs, through the skin barrier. TD-1 can significantly improve the transdermal delivery efficiency of protein drugs such as insulin and human growth hormone, allowing them to reach systemic circulation. Research on TD-1 transdermal drug delivery system[1].
[References]

[1] Chen Y, et al. Transdermal protein delivery by a coadministered peptide identified via phage display[J]. Nature biotechnology, 2006, 24(4): 455-460. DOI:10.1038/nbt1193
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