| Identification | Back Directory | [Name]
CP 66713 | [CAS]
91896-57-0 | [Synonyms]
CP 66713
PF-1716311
4-Amino-8-chloro-1-phenyl[1,2,4]triazolo[4,3-a]quinoxaline
8-chloro-1-phenyl-[1,2,4]triazolo[4,3-a]quinoxalin-4-amine
[1,2,4]Triazolo[4,3-a]quinoxalin-4-amine, 8-chloro-1-phenyl- | [Molecular Formula]
C15H10ClN5 | [MDL Number]
MFCD17215961 | [MOL File]
91896-57-0.mol | [Molecular Weight]
295.73 |
| Chemical Properties | Back Directory | [density ]
1.54±0.1 g/cm3(Predicted) | [storage temp. ]
2-8°C | [solubility ]
DMSO: ≥5mg/mL | [form ]
powder | [pka]
0.68±0.30(Predicted) | [color ]
white to off-white | [InChI]
1S/C15H10ClN5/c16-10-6-7-11-12(8-10)21-14(9-4-2-1-3-5-9)19-20-15(21)13(17)18-11/h1-8H,(H2,17,18) | [InChIKey]
PBENJWAFQLORQL-UHFFFAOYSA-N | [SMILES]
Nc1nc2ccc(Cl)cc2n3c(nnc13)-c4ccccc4 |
| Safety Data | Back Directory | [Hazard Codes ]
Xn | [Risk Statements ]
22-36/37/38 | [Safety Statements ]
26 | [WGK Germany ]
3 | [Storage Class]
11 - Combustible Solids | [Hazard Classifications]
Acute Tox. 4 Oral
Eye Irrit. 2
Skin Irrit. 2
STOT SE 3 |
| Hazard Information | Back Directory | [Uses]
CP-66713 is a selective adenosine A2 receptor antagonist, with Ki of 22 nM. CP-66713 inhibits induction of long-term potentiation of evoked synaptic potentials. CP-66713 can be used in the study of neurological diseases[1]. | [Biological Activity]
CP-66713 is an adenosine A2 receptor antagonist. | [References]
[1] Sekino Y, et al. Adenosine (A2) antagonist inhibits induction of long-term potentiation of evoked synaptic potentials but not of the population spike in hippocampal CA1 neurons. Biochem Biophys Res Commun. 1991 Dec 31;181(3):1010-4. DOI:10.1016/0006-291x(91)92037-k |
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