| Identification | Back Directory | [Name]
ACETHION | [CAS]
919-54-0 | [Synonyms]
ent25650 ACETHION acethione ethoxyphas ethoxyphos prothion[qr] hercules4580 azethion[qr] hercules4580[qr] ethyl((diethoxyphosphinothioyl)thio)acetate o,o-diethyls-carboethoxymethyldithiophosphate ethyl((diethoxyphosphinothioyl)thio)acetate[qr] o,o-diethyls-carboethoxymethylphosphorodithioate o,o-diethyls-carboethoxymethyldithiophosphate[qr] ((diethoxyphosphinothioyl)thio)-aceticaciethylester o,o-diethyls-carboethoxymethylphosphorodithioate[qr] Acetic acid, 2-[(diethoxyphosphinothioyl)thio]-, ethyl ester Dithiophosphoric acid O,O-diethyl S-[(ethoxycarbonyl)methyl] ester phosphorodithioicacid,o,o-diethylester,s-esterwithethylmercaptoacetate aceticacid,mercapto-,ethylester,s-esterwitho,o-diethylphosphorodithioat | [Molecular Formula]
C8H17O4PS2 | [MDL Number]
MFCD00543034 | [MOL File]
919-54-0.mol | [Molecular Weight]
272.32 |
| Hazard Information | Back Directory | [Description]
Acethion is an organophosphate insecticide that is not generally approved for use in the developed world. It is moderately toxic to mammals and a neurotoxin. It is moderately soluble in water and highly volatile. Data related to the environmental degradation of acethion is scarce, as is information on its ecotoxicology. | [Production Methods]
Acethion is commercially produced through the esterification of mercaptoacetic acid with O,O-diethyl phosphorodithioate under controlled conditions to form ethyl 2-(diethoxyphosphinothioylthio)acetate. The synthesis involves reacting mercaptoacetic acid ethyl ester with diethyl phosphorodithioic chloride in an organic solvent such as toluene or dichloromethane, using a base like triethylamine to neutralize the hydrochloric acid byproduct. The reaction is conducted at low to moderate temperatures to preserve the integrity of the organophosphorus structure. | [Mechanism of action]
Non-systemic. Acetylcholinesterase (AchE) inhibitor. | [Pesticide Type]
Insecticide |
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