| Identification | Back Directory | [Name]
Afegostat tartrate | [CAS]
919364-56-0 | [Synonyms]
Afegostat tartrate
Afegostat tartrate/AT 2101/D-Isofagomine tartrate/Isofagomine tartrate | [Molecular Formula]
C10H19NO9 | [MOL File]
919364-56-0.mol | [Molecular Weight]
297.26 |
| Hazard Information | Back Directory | [Uses]
Afegostat tartrate is a pharmacological chaperone, which specifically and reversibly binds acid-β-glucosidase (GCase) in the endoplasmic reticulum (ER) with high affinity[1]. | [References]
[1] Richter F, et al. A GCase chaperone improves motor function in a mouse model of synucleinopathy. Neurotherapeutics. 2014 Oct;11(4):840-56. DOI:10.1007/s13311-014-0294-x |
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