Identification | Back Directory | [Name]
5(S)-HEPE | [CAS]
92008-51-0 | [Synonyms]
5(S)-HEPE 5(S)-HEPE MaxSpecStandard FTAGQROYQYQRHF-GHWNLOBHSA-N 5S-HYDROXY-6E,8Z,11Z,14Z,17Z-EICOSAPENTAENOIC ACID (6E,8Z,11Z,14Z,17Z)-5-hydroxyicosa-6,8,11,14,17-pentaenoic acid | [Molecular Formula]
C20H30O3 | [MDL Number]
MFCD00065812 | [MOL File]
92008-51-0.mol | [Molecular Weight]
318.45 |
Chemical Properties | Back Directory | [Boiling point ]
488.0±45.0 °C(Predicted) | [density ]
0.997±0.06 g/cm3(Predicted) | [storage temp. ]
Store at -20°C | [solubility ]
0.1 M Na2CO3: 2 mg/ml,DMF: Miscible,DMSO: Miscible,Ethanol: Miscible,PBS pH 7.2: 0.8 mg/ml | [pka]
4.67±0.10(Predicted) |
Hazard Information | Back Directory | [Uses]
5(S)-HEPE is produced by 5-lipoxygenase catalyzed oxidation of eicosapentaenoic acid (EPA). While the synthesis of 5(S)-HEPE from EPA by tissue homogenates has been demonstrated, the biological activity of 5(S)-HEPE is poorly documented. It remains to be determined whether this activity differs substantially from that of 5(S)-HETE . | [Definition]
ChEBI: 5S-HEPE is a HEPE. | [IC 50]
Human Endogenous Metabolite | [storage]
Store at -20°C |
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