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92104-54-6

92104-54-6 Structure

92104-54-6 Structure
IdentificationBack Directory
[Name]

2-Amino-6-allylthio-9-(beta-D-ribofuranosyl)-9H-purine
[CAS]

92104-54-6
[Synonyms]

6-S-Allyl-6-thio-guanosine
2-Amino-6-allylthio-9-(beta-D-ribofuranosyl)-9H-purine
9H-Purine, 6-(allylthio)-2-amino-9-β-D-ribofuranosyl- (7CI)
2-Amino-6-allylthio-9-(beta-D-ribofuranosyl)-9H-purine, 6-S-Allyl-6-thio-guanosine
[Molecular Formula]

C13H17N5O4S
[MDL Number]

MFCD31814018
[MOL File]

92104-54-6.mol
[Molecular Weight]

339.37
Chemical PropertiesBack Directory
[Boiling point ]

717.0±70.0 °C(Predicted)
[density ]

1.78±0.1 g/cm3(Predicted)
[pka]

13.08±0.70(Predicted)
Hazard InformationBack Directory
[Uses]

2-Amino-6-allyl thio-9-(beta-D-ribofuranosyl)-9H-purine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].
[References]

[1] Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18(23):3373-88. DOI:10.2174/138161212801227005
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