| Identification | Back Directory | [Name]
12-METHOXYDODECANOIC ACID | [CAS]
92169-28-3 | [Synonyms]
12-methoxydodecanoate
12-METHOXYDODECANOIC ACID
Dodecanoic acid, 12-methoxy-
12-methoxydodecanoic acid sodium | [Molecular Formula]
C13H26O3 | [MDL Number]
MFCD00899847 | [MOL File]
92169-28-3.mol | [Molecular Weight]
230.34 |
| Chemical Properties | Back Directory | [Melting point ]
45-46℃ | [Boiling point ]
336.4±15.0 °C(Predicted) | [density ]
0.943±0.06 g/cm3(Predicted) | [solubility ]
Soluble in ethanol or DMSO at 25mg/ml. | [form ]
White to off-white solid. | [pka]
4.78±0.10(Predicted) |
| Hazard Information | Back Directory | [Uses]
12-Methoxydodecanoic acid, a heteroatom-containing analog of myristic acid, possesses anti-viral activity against HIV, with an IC50 of 6.8 μM. 12-Methoxydodecanoic acid inhibits moloney murine leukemia virus (MoMLV)[1][2]. | [References]
[1] C Pidgeon, et al. Antiviral phospholipids. Anti-HIV drugs conjugated to the glycerobackbone of phospholipids. J Biol Chem. 1993 Apr 15;268(11):7773-8. PMID:7681828
[2] N M Carballeira, et al. New advances in the chemistry of methoxylated lipids. Prog Lipid Res. 2002 Nov;41(6):437-56. DOI:10.1016/s0163-7827(02)00005-x
[3] K Parang, et al. In vitro antiviral activities of myristic acid analogs against human immunodeficiency and hepatitis B viruses. Antiviral Res. 1997 May;34(3):75-90. DOI:10.1016/s0166-3542(96)01022-4 |
|
|