| Identification | Back Directory | [Name]
AC-LEHD-PNA | [CAS]
921771-40-6 | [Synonyms]
AC-LEHD-PNA
AC-LEU-GLU-HIS-ASP-PNA
CASPASE-9 SUBSTRATE (CHROMOGENIC)
CASPASE 9 SUBSTRATE 1, CHROMOGENIC
AC-LEU-GLU-HIS-ASP-PARANITROANILIDE
CASPASE-9 SUBSTRATE II, COLORIMETRIC
N-ACETYL-LEU-GLU-HIS-ASP-P-NITROANILIDE PNA
AC-LEHD-PNA;AC-LEU-GLU-HIS-ASP-PNA;CASPASE-9 CHROMOGENIC SUBSTRATE I | [Molecular Formula]
C29H38N8O11 | [MDL Number]
MFCD02094704 | [MOL File]
921771-40-6.mol | [Molecular Weight]
674.66 |
| Chemical Properties | Back Directory | [Boiling point ]
1245.746±65.00 °C(Press: 760.00 Torr)(predicted) | [density ]
1.410±0.06 g/cm3(Temp: 25 °C; Press: 760 Torr)(predicted) | [storage temp. ]
-20°C | [solubility ]
DMSO: 5mg/mL | [form ]
lyophilized | [pka]
4.014±0.10(predicted) | [color ]
White to off-white | [Sequence]
Ac-Leu-Glu-His-Asp-{pNA} |
| Hazard Information | Back Directory | [Uses]
Caspase 9 is an initiator caspase th at cleaves procaspase 3 and procaspase 7 to propagate the apoptotic cascade. Caspase 9 may be detected using a variety of chromogenic and fluorogenic peptide substrates built around the LEHD peptide core such as the chromogenic substrate Ac-LEHD-pNa (Ac-Leu-Glu-His-Asp-p-nitroanalide). | [Biological Activity]
Cell permeable: no''Primary Target
Caspase-9''Product does not compete with ATP.''Reversible: no |
|
| Company Name: |
Enzo Biochem Inc
|
| Tel: |
Enzo Biochem Inc. 13797054060 |
| Website: |
www.enzo.com |
| Company Name: |
Merck KGaA
|
| Tel: |
21-20338288 |
| Website: |
www.sigmaaldrich.cn |
|