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Tec-IN-6 is a Tec kinase inhibitor. Tec-IN-6 also blocks unconventional secretion of fibroblast growth factor 2 (FGF2). | [Uses]
Tec-IN-6 (compound 6) is a FGF2 binding to Tec kinase inhibitor, with an IC50 of 8.9 μM (His-FGF2/GST-NΔ173 Tec)[1]. | [References]
[1] Giuseppe La Venuta, et al. Small Molecule Inhibitors Targeting Tec Kinase Block Unconventional Secretion of Fibroblast Growth Factor 2. J Biol Chem. 2016 Aug 19;291(34):17787-803. DOI:10.1074/jbc.M116.729384 |
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