| Identification | Back Directory | [Name]
1-[(4-CHLOROPHENYL)METHYL]-1H-INDOLE-3-METHANOL | [CAS]
92407-91-5 | [Synonyms]
NSC741909
NSC-741909
NSC 741909
[1-(4-Chloro-benzyl)-1H-indol-3-yl]-methanol
1-[(4-CHLOROPHENYL)METHYL]-1H-INDOLE-3-METHANOL
1H-INDOLE-3-METHANOL, 1-[(4-CHLOROPHENYL)METHYL]- | [Molecular Formula]
C16H14ClNO | [MDL Number]
MFCD09754713 | [MOL File]
92407-91-5.mol | [Molecular Weight]
271.74 |
| Hazard Information | Back Directory | [Description]
NSC-741909 is an anticancer agent. It acts by suppressing the growth of several cell lines derived from lung, colon, breast, ovarian, and kidney cancers. | [Uses]
Oncrasin-60 (NSC-741909) is a compound with antitumor activity that is active against multiple cancer cell lines in vitro and can induce tumor regression in vivo, with its mechanism involving JNK activation and STAT3 inhibition. | [References]
[1] Antitumor activity of a novel oncrasin analogue is mediated by JNK activation and STAT3 inhibition DOI:10.1371/journal.pone.0028487 |
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