| Identification | Back Directory | [Name]
Pravadoline | [CAS]
92623-83-1 | [Synonyms]
WIN-48098
Pravadoline
Pravadolina
Pravadolinum
Pravadoline [inn]
Pravadoline(WIN 48098)
WIN-48098 (Pravadoline)
Pravadolinum [inn-latin]
Pravadolina [INN-Spanish]
(2-methyl-1-(2-morpholinoethyl)
3-(4-Methoxybenzoyl)-2-methyl-1-(2-morpholinoethyl)-1H-indole
(4-methoxyphenyl)(2-methyl-1-(2-morpholinoethyl)-1H-indol-3-yl)methanone
(4-Methoxyphenyl)-[2-methyl-1-(2-morpholin-4-ylethyl)indol-3-yl]methanone
(4-Methoxyphenyl)(2-methyl-1-(2-(4-morpholinyl)ethyl)-1H-indol-3-yl)methanone
Methanone, (4-methoxyphenyl)(2-methyl-1-(2-(4-morpholinyl)ethyl)-1H-indol-3-yl)- | [Molecular Formula]
C23H26N2O3 | [MDL Number]
MFCD00864378 | [MOL File]
92623-83-1.mol | [Molecular Weight]
378.46 |
| Chemical Properties | Back Directory | [Melting point ]
104-105 °C(Solv: ethyl acetate (141-78-6); hexane (110-54-3)) | [Boiling point ]
553.1±50.0 °C(Predicted) | [density ]
1.18±0.1 g/cm3(Predicted) | [solubility ]
DMF: 5 mg/ml; DMSO: 5 mg/ml; DMSO:PBS (pH 7.2) (1:10): 0.1 mg/ml; Ethanol: 0.15 mg/ml | [form ]
Off-white solid. | [pka]
7.07±0.10(Predicted) | [InChI]
InChI=1S/C23H26N2O3/c1-17-22(23(26)18-7-9-19(27-2)10-8-18)20-5-3-4-6-21(20)25(17)12-11-24-13-15-28-16-14-24/h3-10H,11-16H2,1-2H3 | [InChIKey]
MEUQWHZOUDZXHH-UHFFFAOYSA-N | [SMILES]
C(C1=CC=C(OC)C=C1)(C1C2=C(N(CCN3CCOCC3)C=1C)C=CC=C2)=O |
| Hazard Information | Back Directory | [Uses]
An antiinflammatory and analgesic drug. | [Uses]
Cannabinoid receptor agonist | [Biological Activity]
Pravadoline is a novel analgesic agent whose mechanism of action includes inhibition of cyclooxygenase and cannabinoid receptor agonist activity. |
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