| Identification | Back Directory | [Name]
5-(3-imidazol-1-ylpropylamino)-2-[5-(phenoxymethyl)furan-2-yl]-1,3-oxazole-4-carbonitrile | [CAS]
931704-14-2 | [Synonyms]
5-(3-imidazol-1-ylpropylamino)-2-[5-(phenoxymethyl)furan-2-yl]-1,3-oxazole-4-carbonitrile | [Molecular Formula]
C21H19N5O3 | [MOL File]
931704-14-2.mol | [Molecular Weight]
389.407 |
| Hazard Information | Back Directory | [Uses]
GPX4-IN-12 (compound I22) is a non-covalent GPX4 inhibitor. GPX4-IN-12 induces ferroptosis and inhibits cell growth of HT1080 cells[1]. | [References]
[1] Huang W, et al. Ferroptosis-inducing compounds synergize with docetaxel to overcome chemoresistance in docetaxel-resistant non-small cell lung cancer cells. Eur J Med Chem. 2024 Jul 10;276:116670. DOI:10.1016/j.ejmech.2024.116670 |
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