Identification | Back Directory | [Name]
(2S)-2-[2-[[(1S)-1-carboxy-2-(3H-imidazol-4-yl)ethyl]amino]ethylamino] -5-(diaminomethylideneamino)pentanoic acid | [CAS]
93361-66-1 | [Synonyms]
histargin Nα-[2-[[(S)-4-Guanidino-1-carboxybutyl]amino]ethyl]-L-histidine (2S)-2-[2-[[(1S)-1-carboxy-2-(3H-imidazol-4-yl)ethyl]amino]ethylamino] -5-(diaminomethylideneamino)pentanoic acid | [Molecular Formula]
C14H25N7O4 | [MOL File]
93361-66-1.mol |
Hazard Information | Back Directory | [Description]
Histargin is an enzyme inhibitor isolated from Streptomyces roseoviridis. | [Uses]
Histargin is a carboxypeptidase B inhibitor with IC50 of 17 μg/ml and > 100 μg/ml aganist Carboxypeptidase B and Carboxypeptidase A, respectively. Histargin can be produced by actinomycetes[1]. | [References]
[1] Umezawa H, et al. Histargin, a new inhibitor of carboxypeptidase B, produced by actinomycetes. J Antibiot (Tokyo). 1984 Sep;37(9):1088-90. DOI:10.7164/antibiotics.37.1088 |
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