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935666-99-2

935666-99-2 Structure

935666-99-2 Structure
IdentificationBack Directory
[Name]

(1R)-AZD-1480
[CAS]

935666-99-2
[Synonyms]

(1R)-AZD-1480
[Molecular Formula]

C14H14ClFN8
[MOL File]

935666-99-2.mol
[Molecular Weight]

348.77
Chemical PropertiesBack Directory
[Boiling point ]

575.178±60.00 °C(Press: 760.00 Torr)(predicted)
[density ]

1.518±0.06 g/cm3(Temp: 25 °C; Press: 760 Torr)(predicted)
[form ]

Solid
[pka]

13.553±0.10(predicted)
[color ]

White to off-white
Hazard InformationBack Directory
[Uses]

(1R)-AZD-1480 is the (1R) chiral isomer of AZD-1480, an ATP competitive JAK1 and JAK2 inhibitor[1].
[References]

[1] Derenzini E, et al. The JAK inhibitor AZD1480 regulates proliferation and immunity in Hodgkin lymphoma. Blood Cancer J. 2011 Dec;1(12):e46. DOI:10.1038/bcj.2011.46
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