| Identification | Back Directory | [Name]
CHEMBRDG-BB 4003862 | [CAS]
936940-82-8 | [Synonyms]
CHEMBRDG-BB 4003862
1-(3-fluorophenyl)pyrazole-4-carbaldehyde
1-(3-Fluoro-phenyl)-1H-pyrazole-4-carbaldehyde
1-(3-Fluorophenyl)-1H-pyrazole-4-carboxaldehyde
1H-Pyrazole-4-carboxaldehyde, 1-(3-fluorophenyl)-
1-(3-Fluorophenyl)-1H-pyrazole-4-carbaldehyde AldrichCPR
1-(3-fluorophenyl)-1H-pyrazole-4-carbaldehyde(SALTDATA: FREE) | [Molecular Formula]
C10H7FN2O | [MDL Number]
MFCD05864517 | [MOL File]
936940-82-8.mol | [Molecular Weight]
190.17 |
| Questions And Answer | Back Directory | [Synthesis]
To a 100 mL round-bottom flask, add 1.00 mmol of 1-(3-fluorophenyl)pyrazole, 1.50 mmol of hexamethylenetetramine, and 5 mL of trifluoroacetic acid. Heat the reaction under reflux for 12 hours with stirring. At the end of the reaction, neutralize the resulting solution with 10% NaHCO3 solution in an ice bath, and filter the precipitate under vacuum. If necessary, purify the crude product by column chromatography to obtain 1 g of CHEMBRDG-BB 4003862. | [Application]
1-(3-fluorophenyl)pyrazole-4-carboxaldehyde is an organic intermediate that can be prepared from 1-(3-fluorophenyl)pyrazole via a one-step reaction. 1-(3-fluorophenyl)pyrazole-4-carboxaldehyde can be used to prepare bromine domain protein inhibitors. |
| Chemical Properties | Back Directory | [Boiling point ]
316.9±22.0 °C(Predicted) | [density ]
1.24±0.1 g/cm3(Predicted) | [storage temp. ]
2-8°C | [form ]
solid | [pka]
-2.95±0.12(Predicted) | [InChI]
1S/C10H7FN2O/c11-9-2-1-3-10(4-9)13-6-8(7-14)5-12-13/h1-7H | [InChIKey]
FKZJADFSOBJBNG-UHFFFAOYSA-N | [SMILES]
O=C([H])C1=CN(C2=CC=CC(F)=C2)N=C1 | [CAS DataBase Reference]
936940-82-8 |
|
| Company Name: |
J & K SCIENTIFIC LTD.
|
| Telephone: |
18210857532 18210857532 |
| Website: |
https://www.jkchemical.com |
| Company Name: |
Sigma-Aldrich
|
| Telephone: |
021-61415566 800-8193336 |
| Website: |
https://www.sigmaaldrich.cn |
| Company Name: |
Grader reagent
|
| Telephone: |
18221735425 |
| Website: |
www.shxinping.net |
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