| Identification | Back Directory | [Name]
phenylsulfate | [CAS]
937-34-8 | [Synonyms]
phenylsulfate
Phenol sulfate
Sulfuric acid phenyl
Phenol hydrogen sulfate
Sulfuric acid phenyl ester
Sulfuric acid, Monophenyl ester
Sulfuric acid hydrogen phenyl ester | [Molecular Formula]
C6H6O4S | [MDL Number]
MFCD00059840 | [MOL File]
937-34-8.mol | [Molecular Weight]
174.17 |
| Chemical Properties | Back Directory | [density ]
1.508±0.06 g/cm3(Predicted) | [solubility ]
DMSO: 17.4mg/mL; Water: 37.75mg/mL | [form ]
A solid | [pka]
-4.29±0.15(Predicted) | [color ]
White to off-white |
| Hazard Information | Back Directory | [Uses]
Phenyl sulfate is an orally active gut microbiota-derived metabolite. Phenyl sulfate induces albuminuria and podocyte damage in experimental models of diabetes. Phenyl sulfate can be used as a disease marker and future therapeutic target in diabetic kidney disease[1]. | [Definition]
ChEBI: An aryl sulfate that is phenol bearing an O-sulfo substituent. | [References]
[1] Kikuchi K, et al. Gut microbiome-derived phenyl sulfate contributes to albuminuria in diabetic kidney disease. Nat Commun. 2019 Apr 23;10(1):1835. DOI:10.1038/s41467-019-09735-4 |
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