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93768-49-1

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93768-49-1 Structure

93768-49-1 Structure

Identification	Back Directory
[Name] I5B2
[CAS] 93768-49-1
[Synonyms] I5B2 Antibiotic I5B2
[Molecular Formula] C23H32N3O7P
[MDL Number] MFCD32643426
[MOL File] 93768-49-1.mol
[Molecular Weight] 493.49

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[density ] 1.334±0.06 g/cm3(Predicted)
[pka] 2.55±0.10(Predicted)

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[Description] I5B2 is a new phosphorus containing inhibitor of angiotensin I converting enzyme produced by Actinomadura sp.
[Uses] I5B2 is an angiotensin I converting enzyme inhibitor (IC50=0.091 μM) that can be isolated from the culture medium of Actinomycete actininadura sp. No. 937ZE-1. I5B2 can be used in the study of hypertension[1].
[References] [1] KIDO, et al. "Isolation and characterization of I5B2, a new phosphorus containing inhibitor of angiotensin I converting enzyme produced by Actinomadura sp." The Journal of antibiotics 37.9 (1984): 965-969. DOI:10.7164/antibiotics.37.965

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