ChemicalBook--->CAS DataBase List--->938444-93-0

938444-93-0

938444-93-0 Structure

938444-93-0 Structure
IdentificationBack Directory
[Name]

D-106669
[CAS]

938444-93-0
[Synonyms]

D-106669
N-Ethyl-N'-[3-[(4-methylphenyl)amino]pyrido[2,3-b]pyrazin-6-yl]urea
Urea, N-ethyl-N'-[3-[(4-methylphenyl)amino]pyrido[2,3-b]pyrazin-6-yl]-
[Molecular Formula]

C17H18N6O
[MDL Number]

MFCD17169985
[MOL File]

938444-93-0.mol
[Molecular Weight]

322.36
Chemical PropertiesBack Directory
[Boiling point ]

518.3±50.0 °C(Predicted)
[density ]

1.321
[pka]

10.56±0.43(Predicted)
Hazard InformationBack Directory
[Uses]

D-106669 (comppun 150) is a potent inhibitor of PI3Kα, with the IC50 of 0.129 μM. D-106669 plays an important role in cancer research[1][2].
[IC 50]

PI3Kα: 0.129 μM (IC50)
[References]

[1] Seipelt Irene, et al. Preparation of pyridopyrazines as kinase modulators. United States, US20070123494 A1 2007-05-31.
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