| Identification | Back Directory | [Name]
Midesteine | [CAS]
94149-41-4 | [Synonyms]
MR 889
Midesteine
N-[(Tetrahydro-2-oxothiophen)-3-yl]-2-[[(thiophen-2-yl)carbonyl]thio]propionamide
2-Thiophenecarbothioic acid, S-[1-methyl-2-oxo-2-[(tetrahydro-2-oxo-3-thienyl)amino]ethyl] ester | [Molecular Formula]
C12H13NO3S3 | [MDL Number]
MFCD00867668 | [MOL File]
94149-41-4.mol | [Molecular Weight]
315.43 |
| Hazard Information | Back Directory | [Uses]
Midesteine (MR 889) is a proteinase inhibitor that can inhibit porcine pancreatic elastase, human neutrophil elastase and bovine chymotrypsin. Midesteine has the potential for chronic obstructive pulmonary disease (COPD) and chronic bronchitis research[1]. | [References]
[1] M Luisetti, et al. Studies of MR 889, a new synthetic proteinase inhibitor. Biochem Biophys Res Commun. 1989 Dec 15;165(2):568-73. DOI:10.1016/s0006-291x(89)80004-x
[2] M Luisetti, et al. MR889, a neutrophil elastase inhibitor, in patients with chronic obstructive pulmonary disease: a double-blind, randomized, placebo-controlled clinical trial. Eur Respir J. 1996 Jul;9(7):1482-6. DOI:10.1183/09031936.96.09071482 |
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| Company Name: |
Leancare Ltd.
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| Tel: |
+33 962096793 |
| Website: |
www.leancare.co.uk |
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