| Identification | Back Directory | [Name]
11-Oxomogroside II A1 | [Synonyms]
11-Oxomogroside II A1
19-Norlanost-5-en-11-one, 24-[(6-O-β-D-glucopyranosyl-β-D-glucopyranosyl)oxy]-3,25-dihydroxy-9-methyl-, (3β,9β,10α,24R)- | [Molecular Weight]
799.01 |
| Hazard Information | Back Directory | [Uses]
11-Oxomogroside II A1 (compound 7) is an oxidized cucurbitin. It can be isolated from the ethanol extract of Rohanberry fruit. 11-Oxomogroside II A1 inhibits the activation of Epstein-Barr virus (EBV) early antigen (EBV-EA) induced by 12-O-tetradecanoylphorbol-13-acetate (TPA). 11-Oxomogroside II A1 also weakly inhibits the activation of (±)-(E)-methyl-2-[(E)-hydroxyimino]-5-nitro-6-methoxy-3-hexemide (NOR 1), a nitric oxide (NO) donor[1]. | [References]
[1] Akihisa T, et al. Cucurbitane glycosides from the fruits of Siraitia gros venorii and their inhibitory effects on Epstein-Barr virus activation. J Nat Prod. 2007 May;70(5):783-8. DOI:10.1021/np068074x |
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