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94367-34-7

94367-34-7 Structure

94367-34-7 Structure
IdentificationBack Directory
[Name]

H-Met-AMC
[CAS]

94367-34-7
[Synonyms]

H-Met-AMC
L-Methionine 7-amido-4-methylcoumarin
(2S)-2-amino-N-(4-methyl-2-oxochromen-7-yl)-4-methylsulfanylbutanamide
Butanamide,2-amino-N-(4-methyl-2-oxo-2H-1-benzopyran-7-yl)-4-(methylthio)-,(2S)-
[Molecular Formula]

C15H18N2O3S
[MDL Number]

MFCD00080239
[MOL File]

94367-34-7.mol
[Molecular Weight]

306.38
Chemical PropertiesBack Directory
[Boiling point ]

560.6±50.0 °C(Predicted)
[density ]

1.299±0.06 g/cm3(Predicted)
[solubility ]

Soluble in DMF, DMSO, acetonitrile, ethyl acetate. Slightly soluble in chloroform. Insoluble in water, diethyl ether
[pka]

12.82±0.20(Predicted)
[Appearance]

off-white crystals
Hazard InformationBack Directory
[Description]

H-Met-AMC (L-methionine-7-amido-4-methylcoumarin) is a fluorogenic substrate for methionine aminopeptidase 2 (MetAP2) (Km=310 µM) and aminopeptidase N (Km=377 µM). This substrate is a useful tool for inhibitor screening and kinetic analysis.


H-Met-AMC has an excitation peak at 341 nm and emission at 441 nm. The following excitation/emission can also be used: 355,375/440,450.

[Abs/Em Maxima]

341/441 nm
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