| Hazard Information | Back Directory | [Description]
SHR-110008, also known as Felotaxel, is a microtubule inhibitor potentially for the treatment of cancer. | [Uses]
Felotaxel (SHR110008) is a derivate of Docetaxel (HY-B0011), with antitumor activity and specific pharmacokinetic properties in rats. Felotaxel is rapidly distributed to normal tissues. The kidney is the major excretion organ, and its plasma protein binding capacity is nearly linearly related to concentration. | [References]
[1] Preclinical pharmacokinetic analysis of felotaxel (SHR110008), a novel derivative of docetaxel, in rats and its protein binding ability in vitro DOI:10.1016/j.biopha.2011.11.012 |
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