| Identification | Back Directory | [Name]
3,4-Dimethylbenzylbromide | [CAS]
94416-66-7 | [Synonyms]
4-(broMoMethyl)-1,2-diMethylbenzene
Benzene, 4-(bromomethyl)-1,2-dimethyl- | [Molecular Formula]
C9H11Br | [MDL Number]
MFCD06136695 | [MOL File]
94416-66-7.mol | [Molecular Weight]
199.09 |
| Chemical Properties | Back Directory | [Boiling point ]
237.4±9.0℃ (760 Torr) | [density ]
1.314±0.06 g/cm3 (20 ºC 760 Torr) | [Fp ]
103.2±11.8℃ | [storage temp. ]
Storage temp. 2-8°C | [Appearance]
Off-white to light yellow Solid |
| Hazard Information | Back Directory | [Synthesis]
3,4-Dimethylbenzyl alcohol (1.00 g, 7.34 mmol) was dissolved in dichloromethane (10 mL) at 0 °C and tribromophosphine (1.2 g, 4.41 mmol) was added slowly, keeping the reaction mixture stirred for 3 h at this temperature. Upon completion of the reaction, the reaction was quenched with deionized water (20 mL) followed by extraction with dichloromethane (20 mL x 3). The organic phases were combined, washed with saturated saline (40 mL), dried over anhydrous sodium sulfate and concentrated under reduced pressure to afford 3,4-dimethylbenzyl bromide as a colorless oil (1.2 g, yield: 82%). The product was characterized by 1H NMR (400 MHz, CDCl3) with chemical shifts of δ 7.17 (s, 1H), 7.15-7.09 (m, 2H), 4.47 (s, 2H), 2.25 (s, 6H) ppm. | [References]
[1] Organic and biomolecular chemistry, 2003, vol. 1, # 17, p. 3033 - 3037
[2] Polish Journal of Chemistry, 2007, vol. 81, # 5-6, p. 947 - 969
[3] Patent: WO2013/81642, 2013, A1. Location in patent: Page/Page column 94
[4] Chemical & Pharmaceutical Bulletin, 1983, vol. 31, # 11, p. 4189 - 4192
[5] Pest Management Science, 2000, vol. 56, # 10, p. 875 - 881 |
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