| Chemical Properties | Back Directory | [Boiling point ]
596.0±50.0 °C(predicted) | [density ]
1.15±0.1 g/cm3(Temp: 20 °C; Press: 760 Torr)(predicted) | [form ]
Solid | [pka]
15.17±0.20(predicted) | [color ]
White to off-white |
| Hazard Information | Back Directory | [Uses]
E6-272 is an inhibitor for human papillomavirus 16 (HPV 16). E6-272 inhibits the proliferation of HPV-positive cells SiHa and CaSki with GI50 of 32 nM and 62 nM. E6-272 induces apoptosis in cell SiHa and CaSki[1]. | [References]
[1] Kumar A. Human papillomavirus-16 E6-positive cervical cancer attenuated by potent 2-(4-biphenylyl)-N-(1-ethyl-4-piperidinyl) acetamide second-generation analogs with improved binding affinity. Biotechnol Appl Biochem. 2024 Jul 22. DOI:10.1002/bab.2639 |
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