ChemicalBook--->CAS DataBase List--->94535-50-9

94535-50-9

Request For Quotation
94535-50-9 Structure

94535-50-9 Structure
IdentificationBack Directory
[Name]

LEVCROMAKALIM
[CAS]

94535-50-9
[Synonyms]

brl38227
lemakalim
Brn 3622889
LevkroMakaliM
levcromakelim
LEVCROMAKALIM
(3s-trans)-yrrolidinyl)
Potassium Channel,KcsA,Inhibitor,inhibit,BRL38227,BRL-38227,Levcromakalim
(3β,4α)-3-Hydroxy-2,2-dimethyl-4-(2-oxopyrrolidin-1-yl)chroman-6-carbonitrile
(3S,4R)-3-hydroxy-2,2-dimethyl-4-(2-oxopyrrolidin-1-yl)chroman-6-carbonitrile
2h-1-benzopyran-6-carbonitrile,3,4-dihydro-3-hydroxy-2,2-dimethyl-4-(2-oxo-1-p
(3S,4R)-3β-Hydroxy-4-(2-oxopyrrolizino)-2,2-dimethyl-3,4-dihydro-6-cyano-2H-1-benzopyran
(3β,4α)-3,4-Dihydro-3-hydroxy-2,2-dimethyl-4-(2-oxopyrrolidin-1-yl)-2H-1-benzopyran-6-carbonitrile
(3S,4R)-3,4-DIHYDRO-3-HYDROXY-2,2-DIMETHYL-4-(2-OXO-1-PYRROLIDINYL)-2H-1-BENZOPYRAN-6-CARBONITRILE
2H-1-Benzopyran-6-carbonitrile, 3,4-dihydro-3-hydroxy-2,2-dimethyl-4-(2-oxo-1-pyrrolidinyl)-, (3S,4R)-
2H-1-Benzopyran-6-carbonitrile, 3,4-dihydro-3-hydroxy-2,2-dimethyl-4-(2-oxo-1-pyrrolidinyl)-, (3S,trans)-
[Molecular Formula]

C16H18N2O3
[MDL Number]

MFCD00864806
[MOL File]

94535-50-9.mol
[Molecular Weight]

286.33
Chemical PropertiesBack Directory
[Melting point ]

242-244°
[alpha ]

D26 -52.2° (c = 1 in chloroform)
[Boiling point ]

482.3±45.0 °C(Predicted)
[density ]

1.31±0.1 g/cm3(Predicted)
[storage temp. ]

Store at RT
[solubility ]

DMSO: ≤10 mM, soluble
[form ]

solid
[pka]

13.18±0.60(Predicted)
[color ]

White to off-white
Safety DataBack Directory
[Safety Statements ]

22-24/25
[WGK Germany ]

3
[RTECS ]

DJ2177500
Hazard InformationBack Directory
[Uses]

Anti-asthmatic; antihypertensive.
[Definition]

ChEBI: Levcromakalim is a 1-benzopyran.
[Biological Activity]

Active enantiomer of the prototypical K ATP channel opener cromakalim (trans-3,4-dihydro-3-hydroxy-2,2-dimethyl-4-(2-oxo-1-pyrrolidinyl)-2H-1-benzopyran-6-carbonitrile ). Hypotensive and airways relaxant. IC 50 = 490 nM in guinea pig trachea.
[storage]

Store at RT
Spectrum DetailBack Directory
[Spectrum Detail]

LEVCROMAKALIM(94535-50-9)1HNMR
94535-50-9 suppliers list
Company Name: 3B Pharmachem (Wuhan) International Co.,Ltd.  
Telephone: 18930552037
Website: www.chemicalbook.com/showsupplierproductslist13285/0_en.htm
Company Name: Changzhou PBpharmaceutical R&D Co.,Ltd  
Telephone: 086-0519-83990708 18915800124
Website: http://www.pbpharm.com
Company Name: Shenzhen Regent Biochemical Technology Co., Ltd.  
Telephone: 0755-85201366 18938635012
Website: http://www.regentsciences.com/
Company Name: Aikon International Limited  
Telephone: 025-58859352 13913916777
Website: www.aikonchem.com
Company Name: Fan De(Beijing) Biotechnology Co., Ltd.  
Telephone: 15911056312
Website: www.bio-fount.com
Company Name: Changzhou PBpharmaceutical R&D Co.,Ltd   
Telephone: 0519-83990708
Website: www.chemicalbook.com/ShowSupplierProductsList31332/0_EN.htm
Company Name: Shanghai hongqu biomedical technology co. LTD  
Telephone: 88888888888
Website: www.chemicalbook.com/ShowSupplierProductsList873228/0_EN.htm
Company Name: MedBioPharmaceutical Technology Inc  
Telephone: 021-69568360 18916172912
Website: http://www.med-bio.cn/
Company Name: cjbscvictory  
Telephone: 13348960310 13348960310
Website: www.weikeqi-biotech.com/
Company Name: Abmole Bioscience Inc.  
Telephone: 19821158099
Website: www.abmole.cn/
Company Name: Beijing Jin Ming Biotechnology Co., Ltd.  
Telephone: 010-60605840
Website: http://www.jm-bio.com/
Company Name: ChemeGen  
Telephone: 18818260767
Website: https://www.chemegen.com
Company Name: TargetMol Chemicals Inc.  
Telephone: 4008200310 15002144251
Website: https://www.targetmol.cn/
Company Name: Nantong QuanYi Biotechnology Co., Ltd  
Telephone: 0513-66337626 18051384581
Website: https://www.chemhifuture.com/
Company Name: https://hanhongsci.com/  
Telephone: 021-54306202 18917919676
Website: https://www.hanhongsci.com/
Company Name: Nanjing Shizhou Biology Technology Co.,Ltd  
Telephone: 025-85560043 15850508050
Website: http://www.synzest.com
Company Name: Shanghai Yanze Chemical Co., Ltd  
Telephone: 19901447308 19962611955
Website: www.chemicalbook.com/supplier/25096908/
Company Name: RD International Technology Co., Limited  
Telephone: 18024082417
Website: www.ruidiresearch.com
Tags:94535-50-9 Related Product Information
5291-77-0