| Identification | Back Directory | [Name]
Deferitazole | [CAS]
945635-15-4 | [Synonyms]
SPD602
SPD-602
SPD 602
FBS0701
FBS-0701
FBS 0701
Deferitazole
4-Thiazolecarboxylic acid, 4,5-dihydro-2-[2-hydroxy-3-[2-[2-(2-methoxyethoxy)ethoxy]ethoxy]phenyl]-4-methyl-, (4S)- | [Molecular Formula]
C18H25NO7S | [MDL Number]
MFCD30747904 | [MOL File]
945635-15-4.mol | [Molecular Weight]
399.46 |
| Chemical Properties | Back Directory | [Boiling point ]
584.6±60.0 °C(Predicted) | [density ]
1.30±0.1 g/cm3(Predicted) | [solubility ]
Acetonitrile: Slightly soluble: 0.1-1 mg/ml
Ethanol: Sparingly soluble: 1-10 mg/ml | [pka]
1.02±0.40(Predicted) |
| Hazard Information | Back Directory | [Uses]
Deferitazole (FBS 0701) is an orally active iron chelator. Deferitazole shows antimalarial activity and
Can be used for study of malaria [1][2]. | [References]
[1] Hider RC, et al. Deferitazole, a new orally active iron chelator. Dalton Trans. 2015;44(11):5197-5204. DOI:10.1039/c5dt00063g
[2] Ferrer P, et al. Antimalarial iron chelator, FBS0701, shows asexual and gametocyte Plasmodium falciparum activity and single oral dose cure in a murine malaria model. PLoS One. 2012;7(5):e37171. DOI:10.1371/journal.pone.0037171 |
|
|