| Identification | Back Directory | [Name]
Fmoc-L-photo-methionine | [CAS]
945859-89-2 | [Synonyms]
Fmoc-L-photo-methionine
3H-Diazirine-3-butanoic acid, α-[[(9H-fluoren-9-ylmethoxy)carbonyl]amino]-3-methyl-, (αS)- | [Molecular Formula]
C21H21N3O4 | [MDL Number]
MFCD31380717 | [MOL File]
945859-89-2.mol | [Molecular Weight]
379.42 |
| Chemical Properties | Back Directory | [density ]
1.38±0.1 g/cm3(Predicted) | [storage temp. ]
-20°C | [form ]
powder | [pka]
3.83±0.10(Predicted) | [Major Application]
peptide synthesis | [InChIKey]
QKMQUEIDJLPYHS-SFHVURJKSA-N | [SMILES]
N([C@@H](CCC4(N=N4)C)C(=O)O)C(=O)OCC1c2c(cccc2)c3c1cccc3 |
| Hazard Information | Back Directory | [Uses]
Fmoc-L-photo-methionine is a diazirine-containing, Fmoc-protected methionine amino acid and multifunctional photo-crosslinker. Its incorporation into peptides or small-molecule probes and tools allows for photoaffinity labeling of cellular targets and protein-protein interactions upon UV light (～360 nm) irradiation to form a covalent bond. This and other multifunctional probe building blocks will continue to accelerate drug discovery research for probing cellular mechanisms, target ID/validation, and understanding traditionally undruggable targets. An unprotected version is also available as 907375. | [reaction suitability]
reaction type: Fmoc solid-phase peptide synthesis |
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| Company Name: |
Sigma-Aldrich
|
| Tel: |
021-61415566 800-8193336 |
| Website: |
https://www.sigmaaldrich.cn |
| Company Name: |
Merck KGaA
|
| Tel: |
21-20338288 |
| Website: |
www.sigmaaldrich.cn |
|