| Identification | Back Directory | [Name]
2-Chloro-N6-(2-hydroxyethyl)adenosine | [CAS]
948298-76-8 | [Synonyms]
2-Chloro-N6-(2-hydroxyethyl)adenosine
Adenosine, 2-chloro-N-(2-hydroxyethyl)- | [Molecular Formula]
C12H16ClN5O5 | [MDL Number]
MFCD32215168 | [MOL File]
948298-76-8.mol | [Molecular Weight]
345.74 |
| Hazard Information | Back Directory | [Uses]
2-Chloro-N6-(2-hydroxyethyl)adenosine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1]. | [References]
[1] Man S, et al. Potential and promising anticancer drugs from adenosine and its analogs. Drug Discov Today. 2021 Jun;26(6):1490-1500. DOI:10.1016/j.drudis.2021.02.020
[2] Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18(23):3373-88. DOI:10.2174/138161212801227005 |
|
| Company Name: |
T&W GROUP
|
| Tel: |
021-61551611 13296011611 |
| Website: |
www.trustwe.com/ |
|