| Identification | Back Directory | [Name]
ectylurea | [CAS]
95-04-5 | [Synonyms]
Astyn
A18285
Levanil
ectylurea
2-Ethylcrotonylurea
ectylurea USP/EP/BP
2-Ethyl-cis-crotonylurea
(2-Ethyl-cis-crotonyl)urea
cis-2-Ethyl-crotonylharnstoff
(.alpha.-Ethyl-cis-crotonyl)carbamide
(Z)-N-(Aminocarbonyl)-2-ethyl-2-butenamide
2-Butenamide, N-(aminocarbonyl)-2-ethyl-, (Z)- | [EINECS(EC#)]
202-386-8 | [Molecular Formula]
C7H12N2O2 | [MDL Number]
MFCD00868018 | [MOL File]
95-04-5.mol | [Molecular Weight]
156.18 |
| Chemical Properties | Back Directory | [Melting point ]
198°, also reported as mp 191-193° (lower melting form, mp 158°) | [Boiling point ]
280.42°C (rough estimate) | [density ]
1.1832 (rough estimate) | [refractive index ]
1.4880 (estimate) |
| Hazard Information | Back Directory | [Originator]
Nostyn,Ames,US,1956 | [Definition]
ChEBI: Ectylurea is a N-acylurea. | [Manufacturing Process]
54 g of carbromal (2-bromo-2-ethylbutyryl-urea) in 600 cc of isopropanol was
stirred and refluxed for 3 hours with 27.8 g of anhydrous silver oxide. The
reaction mixture was filtered and the silver residue was extracted with 100 cc
of boiling isopropanol. The filtered and dried solids which separated weighed
22.5 g and melted at 189°C to 190.5°C. Concentration of the filtrate yielded
an additional 3.3 g of product which melted at 160°C to 170°C. These two
crops were separately obtained as white needles by crystallization from
alcohol and exhibited slight solubility in water. The first crop gave 21.7 g of 2-
ethyl-cis-crotonyl urea with a melting point of 191°C to 193°C, and the
second crop gave 0.9 g with a melting point of 191°C to 193°C for a total
yield of 42.4 g or 63% of the theoretical. | [Therapeutic Function]
Sedative |
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