| Identification | Back Directory | [Name]
5-amino-1-(2,4-dimethoxyphenyl)-4-(4-methyl-1,3-thiazol-2-yl)-2H-pyrrol-3-one | [CAS]
951945-67-8 | [Synonyms]
5-amino-1-(2,4-dimethoxyphenyl)-4-(4-methyl-1,3-thiazol-2-yl)-2H-pyrrol-3-one
3H-Pyrrol-3-one, 5-amino-1-(2,4-dimethoxyphenyl)-1,2-dihydro-4-(4-methyl-2-thiazolyl)- | [Molecular Formula]
C16H17N3O3S | [MOL File]
951945-67-8.mol | [Molecular Weight]
331.39 |
| Hazard Information | Back Directory | [Uses]
viFSP1 is a species-independent inhibitor of FSP1 that induces ferroptosis in FSP1-dependent cells. viFSP1 targets the highly conserved NAD(P)H binding pocket of FSP1 and directly inhibits FSP1. viFSP1 induces lipid peroxidation and has anticancer activity[1]. | [References]
[1] Nakamura T et al. Integrated chemical and genetic screens unveil FSP1 mechanisms of ferroptosis regulation. Nat Struct Mol Biol. 2023 Nov;30(11):1806-1815. DOI:10.1038/s41594-023-01136-y |
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| Company Name: |
OTAVA chemicals
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| Tel: |
416 305 9979 (Canada) |
| Website: |
www.otavachemicals.com |
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