| Identification | Back Directory | [Name]
Tenosal | [CAS]
95232-68-1 | [Synonyms]
Tenosal 2-(2-thiophenecarboxy)benzoic acid 2-(thiophene-2-carbonyloxy)benzoic acid 2-Thiophenecarboxylic acid, 2-carboxyphenyl ester | [Molecular Formula]
C12H8O4S | [MDL Number]
MFCD00866162 | [MOL File]
95232-68-1.mol | [Molecular Weight]
248.25 |
| Hazard Information | Back Directory | [Uses]
Tenosal is a new compound obtained by esterifying salicylic acid with 2-thiophene-carboxylic acid and displays anti-inflammatory, analgesic and antipyretic properties. | [in vivo]
Tenosal is a new compound obtained by esterifying salicylic acid with 2-thiophene-carboxylic acid and displays anti-inflammatory, analgesic and antipyretic properties. Extraction recovery measured is on average 95.75% for Tenosal, 98.71% for salicylic acid (SA) and 91.11% for TA. In the whole analysis of Tenosal extracted from plasma, the inter-assay coefficient of variation (C.V.) ranges from 1.00 to 5.86% and the intra assay C.V. is 5.01%. The administration of Tenosal allows a higher bioavailability of SA to be achieved than after dosing with ASA[1]. | [storage]
Store at -20°C | [References]
[1] Lucarelli C, et al. Evaluation of 2-(2-thiophenecarboxy)benzoic acid and related active metabolites in biological samples. J Chromatogr. 1992 Jan 3;573(1):150-3. DOI:10.1016/0378-4347(92)80489-d |
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