ChemicalBook--->CAS DataBase List--->95232-68-1

95232-68-1

95232-68-1 Structure

95232-68-1 Structure
IdentificationBack Directory
[Name]

Tenosal
[CAS]

95232-68-1
[Synonyms]

Tenosal
2-(2-thiophenecarboxy)benzoic acid
2-(thiophene-2-carbonyloxy)benzoic acid
2-Thiophenecarboxylic acid, 2-carboxyphenyl ester
[Molecular Formula]

C12H8O4S
[MDL Number]

MFCD00866162
[MOL File]

95232-68-1.mol
[Molecular Weight]

248.25
Chemical PropertiesBack Directory
[storage temp. ]

Store at -20°C
[solubility ]

Soluble in DMSO
Safety DataBack Directory
[Symbol(GHS) ]


GHS07
[Signal word ]

Warning
[Hazard statements ]

H302-H315-H319-H335
[Precautionary statements ]

P261-P305+P351+P338
Hazard InformationBack Directory
[Uses]

Tenosal is a new compound obtained by esterifying salicylic acid with 2-thiophene-carboxylic acid and displays anti-inflammatory, analgesic and antipyretic properties.
[in vivo]

Tenosal is a new compound obtained by esterifying salicylic acid with 2-thiophene-carboxylic acid and displays anti-inflammatory, analgesic and antipyretic properties. Extraction recovery measured is on average 95.75% for Tenosal, 98.71% for salicylic acid (SA) and 91.11% for TA. In the whole analysis of Tenosal extracted from plasma, the inter-assay coefficient of variation (C.V.) ranges from 1.00 to 5.86% and the intra assay C.V. is 5.01%. The administration of Tenosal allows a higher bioavailability of SA to be achieved than after dosing with ASA[1].

[storage]

Store at -20°C
[References]

[1] Lucarelli C, et al. Evaluation of 2-(2-thiophenecarboxy)benzoic acid and related active metabolites in biological samples. J Chromatogr. 1992 Jan 3;573(1):150-3. DOI:10.1016/0378-4347(92)80489-d
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