| Identification | Back Directory | [Name]
KKL-10 | [CAS]
952849-76-2 | [Synonyms]
KKL-10
KKL-10;KKL 10;KKL10
5-bromo-N-(5-(p-tolyl)-1,3,4-oxadiazol-2-yl)thiophene-2-carboxamide
5-bromo-N-[5-(4-methylphenyl)-1,3,4-oxadiazol-2-yl]thiophene-2-carboxamide | [Molecular Formula]
C14H10BrN3O2S | [MDL Number]
MFCD14042211 | [MOL File]
952849-76-2.mol | [Molecular Weight]
364.22 |
| Chemical Properties | Back Directory | [density ]
1.620±0.06 g/cm3(Predicted) | [storage temp. ]
Store at -20°C | [solubility ]
DMSO:2.89(Max Conc. mg/mL);7.93(Max Conc. mM) | [form ]
Solid | [pka]
10.04±0.70(Predicted) | [color ]
White to off-white |
| Hazard Information | Back Directory | [Uses]
KKL-10 is a small-molecule ribosome rescue inhibitor with broad-spectrum antimicrobial activity against bacteria. | [References]
[1] Tyler D P Goralski, et al. Inhibitors of Ribosome Rescue Arrest Growth of Francisella tularensis at All Stages of Intracellular Replication. Antimicrob Agents Chemother. 2016 May 23;60(6):3276-82. DOI:10.1128/AAC.03089-15
[2] Goralski TD, et al. Inhibitors of Ribosome Rescue Arrest Growth of Francisella tularensis at All Stages of Intracellular Replication. Antimicrob Agents Chemother. 2016 May 23;60(6):3276-82. |
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BOC Sciences
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https://www.bocsci.com |
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