| Identification | Back Directory | [Name]
GANODERIC ACID C1 | [CAS]
95311-97-0 | [Synonyms]
GANODERIC ACID C1
GANODERIC ACID C1 USP/EP/BP
GANODERIC ACID C1(P)(PLEASE CALL)
(25R)-7β-Hydroxy-3,11,15,23-tetraoxolanost-8-en-26-oic acid
(25R)-7β-Hydroxy-3,11,15,23-tetraoxo-5α-lanost-8-en-26-oic acid
(7beta,25R)-7-Hydroxy-3,11,15,23-tetraoxo-lanost-8-en-26-oic acid
Lanost-8-en-26-oicacid, 7-hydroxy-3,11,15,23-tetraoxo-, (7b,25R)-
Lanost-8-en-26-oic acid, 7-hydroxy-3,11,15,23-tetraoxo-, (7β,25R)-
(2R,6R)-6-[(5R,7S,10S,13R,14R,17R)-7-hydroxy-4,4,10,13,14-pentamethyl-3,11,15-trioxo-1,2,5,6,7,12,16,17-octahydrocyclopenta[a]phenanthren-17-yl]-2-methyl-4-oxoheptanoic acid | [Molecular Formula]
C30H42O7 | [MDL Number]
MFCD04039841 | [MOL File]
95311-97-0.mol | [Molecular Weight]
514.65 |
| Chemical Properties | Back Directory | [Melting point ]
150～151℃ | [Boiling point ]
688.3±55.0 °C(Predicted) | [density ]
1.22±0.1 g/cm3(Predicted) | [solubility ]
Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc. | [form ]
Powder | [pka]
4.77±0.23(Predicted) | [color ]
White to light yellow |
| Hazard Information | Back Directory | [Uses]
Ganoderic acid C1, a natural compound that could be isolated from G. lucidum, suppresses TNF-α production by murine macrophages (RAW 264.7 cells)[1]. | [Definition]
ChEBI: Ganoderic acid C1 is a triterpenoid. | [target]
NF-kB | MAPK | AP-1 | TNF-α | IFN-γ | IL Receptor | HIV | [References]
[1] Changda Liu, et al. Ganoderic acid C1 isolated from the anti-asthma formula, ASHMI? suppresses TNF-α production by mouse macrophages and peripheral blood mononuclear cells from asthma patients. Int Immunopharmacol. 2015 Aug;27(2):224-31. DOI:10.1016/j.intimp.2015.05.018 |
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