| Identification | Back Directory | [Name]
N6-Benzoyl-7'-OH-N-trityl Morpholino adenosine | [CAS]
956139-16-5 | [Synonyms]
PMO-A Precusor
PMO Adesnosine Precusor
6-Benzoyl-7’-OH-N-trityl morpholino adenosine
N6-Benzoyl-7'-OH-N-trityl Morpholino adenosine
N6-Benzoyl-7'-hydroxy-N-trityl morpholino adenine
N6-Benzoyl-7'-hydroxymorpholino adenosine monomer
N-(9-(6-(hydroxymethyl)-4-tritylmorpholin-2-yl)-9H-purin-6-yl) benzamide
(2′R,6′S)-N6-benzoyl-9-[6′-(hydroxymethyl)-N-tritylmorpholin-2′-yl]adenine
N-(9-[(2R,6S)-6-(Hydroxymethyl)-4-tritylmorpholine-2-yl]-purine-6-yl)benzamide
N-(9-((2R,6S)-6-(hydroxymethyl)-4-tritylmorpholin-2-yl)-9H-purin-6-yl)benzamide
Benzamide, N-[9-[(2R,6S)-6-(hydroxymethyl)-4-(triphenylmethyl)-2-morpholinyl]-9H-purin-6-yl]- | [Molecular Formula]
C36H32N6O3 | [MDL Number]
MFCD22666304 | [MOL File]
956139-16-5.mol | [Molecular Weight]
596.68 |
| Chemical Properties | Back Directory | [InChIKey]
XFQQPEYYQOKYTE-IOWSJCHKSA-N | [SMILES]
C(NC1=C2C(=NC=N1)N([C@@H]1O[C@H](CO)CN(C(C3=CC=CC=C3)(C3=CC=CC=C3)C3=CC=CC=C3)C1)C=N2)(=O)C1=CC=CC=C1 |
| Hazard Information | Back Directory | [Uses]
N6-Benzoyl-7’-OH-N-trityl morpholino adenine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1]. | [References]
[1] Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18(23):3373-88. DOI:10.2174/138161212801227005 |
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