ChemicalBook--->CAS DataBase List--->957772-01-9

957772-01-9

Request For Quotation
957772-01-9 Structure

957772-01-9 Structure
IdentificationBack Directory
[Name]

TP0438836
[CAS]

957772-01-9
[Synonyms]

TP0438836
[Molecular Formula]

C27H38N2O10
[MOL File]

957772-01-9.mol
[Molecular Weight]

550.61
Chemical PropertiesBack Directory
[Boiling point ]

937.9±65.0 °C(Predicted)
[density ]

1.419±0.06 g/cm3(Predicted)
[pka]

10.20±0.10(Predicted)
Hazard InformationBack Directory
[Description]

TP0438836 is a potent, low-absorbable sodium-dependent glucose cotransporter 1 (SGLT1) inhibitor for the treatment of type 2 diabetes. TP0438836 showed IC50 values 28nM and 7 nM for hSGLT1 and hSGLT2 resepctively.
[Uses]

TP0438836 (compound 30b) is a SGLT1 inhibitor, with IC50 values ??of 28 nM and 7 nM for hSGLT1 and hSGLT2, respectively. TP0438836 can be used in diabetes research[1].
[IC 50]

hSGLT1: 28 nM (IC50); hSGLT2: 7 nM (IC50)
[References]

[1] Kuroda S, et al. Discovery of a potent, low-absorbable sodium-dependent glucose cotransporter 1 (SGLT1) inhibitor (TP0438836) for the treatment of type 2 diabetes. Bioorg Med Chem Lett. 2018 Dec 1;28(22):3534-3539. DOI:10.1016/j.bmcl.2018.09.035
957772-01-9 suppliers list
Company Name: TargetMol Chemicals Inc.
Tel: +17819995354 , +17819995354
Website:
Company Name: TargetMol Chemicals Inc.  
Tel: 15002134094
Website: https://www.targetmol.cn/
Tags:957772-01-9 Related Product Information