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95864-17-8

95864-17-8 Structure

95864-17-8 Structure
IdentificationBack Directory
[Name]

1-PALMITOYL-2-PYRENEDECANOYLPHOSPHATIDYLCHOLINE
[CAS]

95864-17-8
[Synonyms]

10-PYRENE-PC
BETA-PY-C10-HPC
1-PALMITOYL-2-PYRENEDECANOYLPHOSPHATIDYLCHOLINE
L-A-PHOSPHATIDYLCHOLINE, B-*(PYREN-1-YL) DECANOYL-
1-palmitoyl-2-(1'-pyreneoctanoyl)glycero-3-phosphochine
3-PalMitoyl-2-(1-pyrenodecanoyl)-L-α-phosphatidylcholine
l-α-phosphatidylcholine, β-(pyren-1-yl)decanoyl-γ-palmitoyl
1-palmitoyl-2-pyrenedecanoyl-sn-glyero-3-phosphatidylcholine
1-palmitoyl-2-(pyrene-1-yl)decanoyl-sn-glycero-3-phosphocholine
1-HEXADECANOYL-2-(1-PYRENEDECANOYL)-SN-GLYCERO-3-PHOSPHOCHOLINE
L-ALPHA-PHOSPHATIDYLCHOLINE, BETA-(PYREN-1-YL)DECANOYL-GAMMA-PALMITOYL
1-O-HEXADECANOYL-2-O-(10-(1-PYRENYL)DECANOYL)-SN-GLYCERYL-3-PHOSPHORYLCHOLINE
β-Py-C10-HPC [1-Hexadecanoyl-2-(1-Pyrenedecanoyl)-sn-Glycero-3-Phosphocholine]
(7R)-4-hydroxy-N,N,N-triMethyl-10-oxo-7-[[1-oxo-10-(1-pyrenyl)decyl]oxy]-3,5,9-Trioxa-4-phosphapentacosan-1-aMiniuM Inner Salt 4-Oxide
[Molecular Formula]

C50H76NO8P
[MDL Number]

MFCD00063542
[MOL File]

95864-17-8.mol
[Molecular Weight]

850.13
Chemical PropertiesBack Directory
[storage temp. ]

−20°C
[solubility ]

Soluble in DMSO
[form ]

powder
[Appearance]

Solid Powder
[InChIKey]

HBCKORABVGGHAT-UHFFFAOYSA-N
[SMILES]

CCCCCCCCCCCCCCCC(=O)OC[C@@H](COP(O)(=O)OCC[N](C)(C)C)OC(=O)CCCCCCCCCc1ccc2ccc3cccc4ccc1c2c34
Safety DataBack Directory
[Symbol(GHS) ]

Skull and Crossbones (GHS06)Exclamation Mark (GHS07)Health Hazard (GHS08)
GHS06,GHS07,GHS08
[Signal word ]

Danger
[Hazard statements ]

H302-H310-H331-H315-H319-H351-H361-H372
[Precautionary statements ]

P201-P202-P260-P262-P264-P270-P271-P280-P301+P312-P302+P352-P304+P340-P305+P351+P338-P310-P308+P313-P321-P314-P330-P361+P364-P332+P313-P337+P313-P403+P233-P405-P501
[WGK Germany ]

3
[Storage Class]

11 - Combustible Solids
Hazard InformationBack Directory
[Description]

10-Pyrene-PC is a substrate for all PLA2s with the exception of cPLA2 and PAF-AH. Upon phospholipid hydrolysis, 10-pyrenyldecanoic acid is produced from 10-pyrene-PC. The monomeric 10-pyrenyldecanoic acid exhibits fluorescence (excitation 345 nm, emission 395 nm), allowing quantitation of phospholipase activity.
[Uses]

1-Palmitoyl-2-pyrenedecanoylphosphatidylcholine is a fluorescent phospholipid used to study the mechanism of spontaneous phospholipid transfer between single-walled phospholipid vesicles (liposomes) and other membrane interactions.
[References]

[1] ROBERTS M F. Phospholipases: structural and functional motifs for working at an interface[J]. FASEB Journal, 1996, 10 10: 1159-1172. DOI: 10.1096/fasebj.10.10.8751718
[2] S LUSA. Degradation of pyrene-labelled phospholipids by lysosomal phospholipases in vitro. Dependence of degradation on the length and position of the labelled and unlabelled acyl chains.[J]. Biochemical Journal, 1996, 315 ( Pt 3): 947-952. DOI: 10.1042/bj3150947
[Excitation / Emission Maximum]

342 nm/376 nm
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