| Identification | Back Directory | [Name]
HUMAN IGF-II | [CAS]
96081-16-2 | [Synonyms]
IGF-II
RHIGF-II
IGF-2 HUMAN
HUMAN IGF-II
IGF-II, HUMAN
Somatamedin A
RH-IGF-II HUMAN
HUMAN SOMATAMEDIN A
RECOMBINANT HUMAN IGF-II
REC IGF-II (1-67) (HUMAN)
INSULIN-LIKE GROWTH FACTOR-II
INSULIN-LIKE GROWTH FACTOR-II HUMAN
HUMAN INSULIN-LIKE GROWTH FACTOR II
Insulin-like Growth Factor-II from mouse
REC INSULIN-LIKE GROWTH FACTOR-II (1-67) (HUMAN)
INSULIN-LIKE GROWTH FACTOR-II, HUMAN, RECOMBINANT
INSULIN-LIKE GROWTH FACTOR-II (IGF-II), HUMAN, RECOMBINANT
(2S)-1-acetyl-N-[(2S,3R)-1-[[(2S)-1-[[(2S)-3,3-dihydroxy-1-(4-hydroxyphenyl)butan-2-yl]amino]-3-hydroxy-1-oxopropan-2-yl]amino]-3-hydroxy-1-oxobutan-2-yl]pyrrolidine-2-carboxamide
ALA-TYR-ARG-PRO-SER-GLU-THR-LEU-CYS-GLY-GLY-GLU-LEU-VAL-ASP-THR-LEU-GLN-PHE-VAL-CYS-GLY-ASP-ARG-GLY-PHE-TYR-PHE-SER-ARG-PRO-ALA-SER-ARG-VAL-SER-ARG-ARG-SER-ARG-GLY-ILE-VAL-GLU-GLU-CYS-CYS-PHE-ARG-SER-CYS-ASP-LEU-ALA-LEU-LEU-GLU-THR-TYR-CYS-ALA-THR-PRO-ALA-LYS-SER-GLU
H-Ala-Tyr-Arg-Pro-Ser-Glu-Thr-Leu-Cys-Gly-Gly-Glu-Leu-Val-Asp-Thr-Leu-Gln-Phe-Val-Cys-Gly-Asp-Arg-Gly-Phe-Tyr-Phe-Ser-Arg-Pro-Ala-Ser-Arg-Val-Ser-Arg-Arg-Ser-Arg-Gly-Ile-Val-Glu-Glu-Cys-Cys-Phe-Arg-Ser-Cys-Asp-Leu-Ala-Leu-Leu-Glu-Thr-Tyr-Cys-Ala-Thr-Pro-Ala-Lys-Ser-Glu-OH | [Molecular Formula]
C24H36N4O9 | [MDL Number]
MFCD00241895 |
| Hazard Information | Back Directory | [Biochem/physiol Actions]
Insulin-like growth factor II (IGF-II) also known as multiplication stimulating activity (MSA), shows virtually identical bioactivities as IGF-I. Expression of IGF-II is highest in fetal tissues, where it is believed to play a major role in overall growth and development. After birth IGF-II expression decreases to much lower levels in a variety of tissues. IGF-II is produced also in several tumors. IGF-II binds to IGF-II receptor (IGF-IIR), to IGF-IR and weakly to the insulin receptor (IR). All IGF-II bioactivities in adult tissues are generally attributed to its interaction with IGF-IR. However, during embryogenesis the roles of both IGF-IIR and IR may be significant in promoting normal growth. |
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