| Identification | Back Directory | [Name]
Lipstatin | [CAS]
96829-59-3 | [Synonyms]
Lipstatin
(-)-Lipstatin
high quality Lipstatin
Lipstatin Solution, 100ppm
Orlistat Tetradehydro Impurity
Orlistat Impurity 23 (Orlistat Tetradehydro Impurity) (Lipstatin)
[(2S,4E,7E)-1-(3-hexyl-4-oxooxetan-2-yl)trideca-4,7-dien-2-yl] (2S)-2-formamido-3-methylpentanoate
N-Formyl-L-leucine (1S,3Z,6Z)-1-[[(2S,3S)-3-hexyl-4-oxo-2-oxetanyl]methyl]-3,6-dodecadien-1-yl ester
L-Leucine, N-formyl-,(1S,3Z,6Z)-1-[[(2S,3S)-3-hexyl-4-oxo-2-oxetanyl]methyl]-3,6-dodecadien-1-ylester
(2S-(2alpha(1R*,3Z,6Z),3beta))-N-Formyl-L-leucine 1-((3-hexyl-4-oxo-2-oxetanyl)methyl)-3,6-dodecadienyl ester
(-)-Lipstatin
N-Formyl-L-leucine (1S,3Z,6Z)-1-[[(2S,3S)-3-hexyl-4-oxo-2-oxetanyl]methyl]-3,6-dodecadien-1-yl ester | [EINECS(EC#)]
619-246-0 | [Molecular Formula]
C29H49NO5 | [MDL Number]
MFCD09838128 | [MOL File]
96829-59-3.mol | [Molecular Weight]
491.7 |
| Chemical Properties | Back Directory | [Boiling point ]
627.4±55.0 °C(Predicted) | [density ]
0.993 | [storage temp. ]
-20°C Freezer, Under Inert Atmosphere | [solubility ]
Chloroform (Slightly), Ethyl Acetate (Slightly), Methanol (Slightly) | [form ]
Oil | [pka]
14.57±0.23(Predicted) | [color ]
Clear Colorless to Light Yellow |
| Hazard Information | Back Directory | [Uses]
Lipstatin is a potent irreversible inhibitor of pancreatic lipase, produced by Streptomyces toxytricini and first reported in 1987. In vivo, lipstatin acts to block the absorption of triglycerides while allowing fatty acid absorption. The tetrahydro analogue of lipstatin, orlistat, although less potent, was developed for the treatment of obesity. | [Uses]
Lipstatin, a potent inhibitor of the pancreas lipase, is reported to be useful in the treatment and/or prevention of obesity and related diseases. |
|
|