Identification | Back Directory | [Name]
KKI 5 | [CAS]
97145-43-2 | [Synonyms]
1G,10G,100G L-Glutamamide, 1-acetyl-L-prolyl-L-phenylalanyl-L-arginyl-L-seryl-L-valyl- (9CI) | [Molecular Formula]
C35H55N11O9 | [MOL File]
97145-43-2.mol | [Molecular Weight]
773.88 |
Chemical Properties | Back Directory | [density ]
1.44±0.1 g/cm3(Predicted) | [form ]
Solid | [pka]
12.94±0.46(Predicted) | [Water Solubility ]
Soluble in water at 1mg/ml | [Sequence]
Ac-Pro-Phe-Arg-Ser-Val-Gln-NH2 |
Hazard Information | Back Directory | [Uses]
KKI-5 is a specific inhibitor of tissue kallikrein. KKI-5 can attenuate breast cancer cell invasion[1]. | [References]
[1] Deshpande MS, et al. Mapping the binding site of tissue kallikrein: preparation and testing of all possible substrate analog inhibitors homologous with the sequence of kininogen between Ser386 and Gln392. J Med Chem. 1992 Aug 21;35(17):3094-102. DOI:10.1021/jm00095a002 |
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BOC Sciences
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https://www.bocsci.com |
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