| Identification | Back Directory | [Name]
2-AMINO-3-NITRO-BENZALDEHYDE | [CAS]
97271-97-1 | [Synonyms]
2-AMINO-3-NITRO-BENZALDEHYDE
Benzaldehyde, 2-aMino-3-nitro- | [Molecular Formula]
C7H6N2O3 | [MDL Number]
MFCD09880173 | [MOL File]
97271-97-1.mol | [Molecular Weight]
166.13 |
| Chemical Properties | Back Directory | [Melting point ]
137-138 °C(Solv: methanol (67-56-1)) | [Boiling point ]
335.8±32.0 °C(Predicted) | [density ]
1.441±0.06 g/cm3(Predicted) | [storage temp. ]
under inert gas (nitrogen or Argon) at 2–8 °C | [pka]
-3.97±0.25(Predicted) | [Appearance]
Yellow to brown Solid |
| Hazard Information | Back Directory | [Synthesis]
General procedure for the synthesis of 2-amino-3-nitrobenzaldehyde from (2-amino-3-nitrophenyl)methanol: Synthesis of 6,7-didehydro-17-methyl-8'-nitroquinolo[2',3':6,7]morphinan-3,14β-diol hydrochloride (SYK-349) from compound 29d with reference to the procedure used for the preparation of SYK-27. The product is a brown amorphous solid with 98% yield and a melting point of 255-262°C (decomposition). Elemental analysis (C24H23N3O4-1.5HCl-0.5H2O) Calculated values: C, 59.91; H, 5.34; N, 8.73. Measured values: C, 60.10; H, 5.42; N, 8.46. | [References]
[1] Bioorganic and Medicinal Chemistry, 2012, vol. 20, # 19, p. 5810 - 5831 |
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